Peptide Coupling Reagent
HONB
N-Hydroxy-5-norbornene-2,3-dicarboximide
- CAS No.
- 21715-90-2
- Molecular formula
- C9H9NO3
- Molecular weight
- 179.18 g/mol
- Appearance
- White to off-white crystalline powder
- Purity
- ≥98% (HPLC)
- Product family
- Peptide Coupling Reagent
Used for
PEPTIDE SYNTHESIS REAGENT
Description
N-Hydroxy-5-norbornene-2,3-dicarboximide (HONB) is a highly efficient coupling reagent intermediate widely used in peptide synthesis.
It enhances reaction efficiency and reduces racemization during peptide coupling processes.
It is commonly used in pharmaceutical research, peptide chemistry, and fine chemical manufacturing industries.
It acts as an additive with carbodiimides like EDC to improve yield and minimize side reactions.
We supply high-purity HONB suitable for research and industrial-scale applications.
Technical specifications
- Melting Point
- 160–165°C
- Moisture Content
- ≤ 0.5%
- Solubility
- Soluble in organic solvents (DMF, DMSO, Methanol)
Packaging & storage
- Storage
- Store in cool, dry place under inert atmosphere
Safety information (GHS)
- Hazard Class: Irritant
- GHS Signal Word: Warning
- Skin Irritation: Category 2
- Eye Irritation: Category 2
- Handling: Handle with gloves and protective equipment; avoid inhalation and direct contact
Synonyms
HONB · Hydroxy Norbornene Imide