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Lifechem Products

1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide Hydrochloride | EDC HCL Manufacturer | India | Italy

EDC HCL, EDC hydrochloride, EDAC Hydrochloride
1-Ethyl-3-(3-Dimethylaminopropyl)Carbodiimide Hydrochloride
Purity (Titration):Min 98.00 %
Mol Formula:C8H17N3 · HCl
Cas no:25952-53-8
1-Ethyl-3-(3-Dimethylaminopropyl)Carbodiimide Hydrochloride
1Peptide Synthesis:
It is widely used in peptide synthesis to couple amino acids and form peptide bonds.
2Protein Modification:
It used to modify proteins by cross-linking carboxyl groups to primary amines.
3Immobilization of Biomolecules:
It is employed in the immobilization of biomolecules on surfaces or matrices.
4Nucleic Acid Research:
It can be used in nucleic acid research for the activation of carboxylic acids on solid supports.
Mechanism of Action
It activates carboxylic acids by converting them into highly reactive O-acylisourea intermediates. These intermediates can then react with nucleophiles, such as amines, to form stable amide bonds.

Safety  Precautions: EDC HCL

EDC hydrochloride should be handled with care as it may irritate the skin, eyes, and respiratory system.
It is recommended to use protective equipment, such as gloves and goggles, when working with this reagent.
Store EDC hydrochloride in a cool, dry place, away from moisture and direct sunlight.
Keep it sealed to prevent contamination.
It is a valuable reagent in various chemical processes, contributing to advancements in peptide synthesis, protein modification, and biomolecule research.
Pre-Sales Service
* Prompt reply and 24 hours online, professional team to provide the best price and high-quality product.
* Sample testing support.
* Every batch of products will be tested to ensure its quality.
* The packing also can be according to the customers` requirement.
* Any inquiries will be replied to within 24 hours.
* We provide a Commerical Invoices, Packing Lists, Bills of loading, COA, Health certificates, and Origin certificates. If your markets have any special requirements, let us know.
Do you accept sample order?
We will make samples before mass production, and after the sample is approved, we’ll begin mass production. Doing 100% inspection during production, then doing random inspection before packing.
What’s your MOQ?
Our MOQ is 1kg. But usually we accept less quantities, such as 100g on the condition that the courier charge is 100% paid.
What is EDC HCl?
EDC HCl is a chemical reagent used for the activation of carboxylic acids during peptide coupling reactions. It facilitates the formation of amide bonds between carboxylic acid and amine groups.
How to confirm the product quality before placing orders?
You can get free samples for some products, you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests, we will manufacture the products according to your requests.
What is the purpose of using EDC HCl in peptide synthesis?
EDC HCl is commonly used to activate carboxylic acids for peptide bond formation in solid-phase peptide synthesis (SPPS) or solution-phase peptide synthesis.
Other Info
Brand:Life Chem Pharma
Provide:1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride (EDC HCL)


CAS No :


EC Number :


Formula :


Product Specification

EDC HCL Specifications

  • Appearance : White to off white powder
  • Solubility: Soluble in water
  • Melting point: 110-116 ºC
  • Purity (Titration) : Min 98.0 %
  • Molecular Formul : C8H17N3·HCl
  • Molecular Weigh : 191.70
  • Density : 0.877 g/mL at 20ºC(lit.)
  • Storage Conditio: Below 25 ºC temperature
  • Transport Conditio : At ambient temperature
  • Pack size : 25 KG
  • Production Capacit : 5 MT per month

Safety Information As Per GHS

Hazard Statement(s) as per GHS | EDC HCL

  • H315: Causes skin irritation.
  • H318: Causes serious eye damage.
  • H335: May cause respiratory irritation