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Tf2O or triflic acid anhydride is the derived from triflic acid. This reagent has appeared recently as a powerful and versatile tool in organic synthesis and has revolutionized pharmaceutical chemistry. Its electrophilic nature and ability to activate a multitude of functional groups have rendered it as a reagent for simplifyingContinue Reading

Peptide synthesis is a complex and often very tightly controlled discipline. The choice of coupling agent is extremely important to afford the efficient construction of the peptide bond while maintaining both purity and scale of production. One of the most famous and one of the most trusted reagents in thisContinue Reading

Chemical Name: Sodium Triacetoxyborohydride Molecular Formula: C6H10BNaO6 CAS Number: 56553-60-7 Molecular Weight: 211.95 g/mol Appearance: White to off-white crystalline powder Solubility: Soluble in organic solvents like dichloromethane, acetonitrile, and THF; insoluble in water General Information Sodium Triacetoxyborohydride is a widely used reducing agent in organic chemistry, particularly for the selectiveContinue Reading

Chemical Name Bromoacetonitrile Molecular Formula C2H2BrN CAS Number 590-17-0 Molecular Weight 118.95 g/mol Appearance Colorless to pale yellow liquid Boiling Point 108°C Density 1.66 g/cm³ Solubility Slightly soluble in water; miscible with organic solvents like ethanol, ether, and chloroform Bromoacetonitrile – General Information Bromoacetonitrile is a highly reactive organobromine compoundContinue Reading

EDC HCL Properties form crystalline Quality Level 200 reaction suitability reagent type: cross-linking reagent reaction type: Peptide Synthesis mp 110-115 °C (lit.) solubility H2O: ≤100 mg/mL storage temp. −20°C SMILES string Cl.CCN=C=NCCCN(C)C InChI 1S/C8H17N3.ClH/c1-4-9-8-10-6-5-7-11(2)3;/h4-7H2,1-3H3;1H InChI key FPQQSJJWHUJYPU-UHFFFAOYSA-N   EDC HCL Introduction: N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide hydrochloride, commonly known as EDC or EDAC, isContinue Reading