N,N-Bis(trifluoromethanesulfonyl)aniline | Methanesulfonamide, 1,1,1-trifluoro-n-phenyl-n-[(Trifluoromethyl)sulfonyl]- | N-phenylbis(Trifluoromethanesulfonyl)imide | 1,1,1-trifluoro-n-phenyl-n-[(Trifluoromethyl)sulfonyl]methanesulfonamide | N-phenylbis(Trifluoromethanesulfonimide) | N-phenyltriflimide | N-phenyl-n-(Trifluoromethanesulfonyl)trifluoromethanesulfonamide | N,n-bis(Trifluoromethylsulfonyl)phenylamine | 1,1,1-trifluoro-n-phenyl-n-(Trifluoromethylsulfonyl)methanesulfonamide | N-phenyltrifluoromethylsulfonimide | Phenyl Bis((Trifluoromethyl)sulfonyl)amine | Nsc 240874 | Trifluoro-n-phenyl-n-[(Trifluoromethyl)sulfonyl]methanesulfonamide | N-phenyl-n-[(Trifluoromethyl)sulfonyl]trifluoromethanesulfonamide | N-phenyltrifluoromethanesulfonimide | Phntf2 | N-phenyl-bis(Trifluoromethanesulfonimide) | 1,1,1-trifluoro-n-phenyl-n-trifluoromethanesulfonylmethanesulfonamide
N-Phenyl-bis(trifluoromethanesulfonimide)(PhNTF2) is a stable, crystalline, and easy-to-handle trifling agent, useful for the triflation of phenols and amines (especially aliphatic secondary amines; aromatic secondary amines). The reagent was introduced for the selective formation of trifluoromethane sulfonates (triflates) from phenols and amines, and it is often superior to trifluoromethanesulfonic anhydride for generating enol triflates from carbonyl compounds.
Triflates of enol and Aryl are activated intermediates that can go through Stille, Suzuki, and other coupling reactions. They are commonly used in ways to create multifunctional, sensitive molecules. The example can be found in the entire syntheses of (+-)-Gelsemine.
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- Appearance & Physical State – white to off-white crystalline powder
- Molecular weight – 357.25000
- Boiling point – 305.3ºC at 760 mmHg
- Flash Point – 138.4ºC
- Smiles – FC(F)(F)[S](=O)(=O)N(c1ccccc1)[S](=O)(=O)C(F)(F)F
- Density – 1.766 g/cm3
- Inchikey- DIOHEXPTUTVCNX-UHFFFAOYSA-N
- Sensitive – Moisture Sensitive
Safety Information As Per GHS
Hazard Statement(s) as per GHS
- H315: Causes skin irritation.
- H319: Causes serious eye irritation
- H335: May cause respiratory irritation