N-phenyl-bis(Trifluoromethane Sulphonimide)

Lifechem Products

N-phenyl-bis(Trifluoromethane Sulphonimide)

N,N-Bis(trifluoromethanesulfonyl)aniline | Methanesulfonamide, 1,1,1-trifluoro-n-phenyl-n-[(Trifluoromethyl)sulfonyl]- | N-phenylbis(Trifluoromethanesulfonyl)imide | 1,1,1-trifluoro-n-phenyl-n-[(Trifluoromethyl)sulfonyl]methanesulfonamide | N-phenylbis(Trifluoromethanesulfonimide) | N-phenyltriflimide | N-phenyl-n-(Trifluoromethanesulfonyl)trifluoromethanesulfonamide | N,n-bis(Trifluoromethylsulfonyl)phenylamine | 1,1,1-trifluoro-n-phenyl-n-(Trifluoromethylsulfonyl)methanesulfonamide | N-phenyltrifluoromethylsulfonimide | Phenyl Bis((Trifluoromethyl)sulfonyl)amine | Nsc 240874 | Trifluoro-n-phenyl-n-[(Trifluoromethyl)sulfonyl]methanesulfonamide | N-phenyl-n-[(Trifluoromethyl)sulfonyl]trifluoromethanesulfonamide | N-phenyltrifluoromethanesulfonimide | Phntf2 | N-phenyl-bis(Trifluoromethanesulfonimide) | 1,1,1-trifluoro-n-phenyl-n-trifluoromethanesulfonylmethanesulfonamide

N-Phenyl-Bis(Trifluoromethane Sulphonimide)

N-Phenyl-bis(trifluoromethanesulfonimide)(PhNTF2) is a stable, crystalline, and easy-to-handle trifling agent, useful for the triflation of phenols and amines (especially aliphatic secondary amines; aromatic secondary amines). The reagent was introduced for the selective formation of trifluoromethane sulfonates (triflates) from phenols and amines, and it is often superior to trifluoromethanesulfonic anhydride for generating enol triflates from carbonyl compounds.

Triflates of enol and Aryl are activated intermediates that can go through Stille, Suzuki, and other coupling reactions. They are commonly used in ways to create multifunctional, sensitive molecules. The example can be found in the entire syntheses of (+-)-Gelsemine.