Methyl Trifluoromethanesulfonate (Methyl Triflate )

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Methyl Trifluoromethanesulfonate (Methyl Triflate )

CAS No :	333-27-7
EC Number :	206-371-7
Formula :	C2H3F3O3S

Category: Triflic Derivatives

Product Specification

Appearance & Physical State – Colourless Liquid
Molecular weight – 164.10400
Boiling point – 95ºC
Flash Point – 38ºC
Density – 1.45 g/mL at 25 °C
Storage Condition – 0-6°C
Sensitive – Air Sensitive

Safety Information As Per GHS

Hazard - 8 corrosive

Hazard Statement(s) as per GHS

H226: Flammable liquid and vapour.
H301 + H311: Toxic if swallowed or in contact with skin.
H314: Causes severe skin burns and eye damage.
H330: Fatal if inhaled.

Methyl Trifluoromethanesulfonate (Methyl Triflate )Methyl trifluoromethanesulfonate, also commonly called methyl triflate and abbreviated MeOTf, is the organic compound with the formula CF3SO2OCH3. It is a colorless liquid that can be used in organic chemistry to act as a chemical methylating agent. It is closely related to the methyl fluorosulfonate (FSO2OCH3). While there is yet to be an official report of human death, several cases have been reported with Fluorosulfonate methyl (LC50 (rat 1 hour) 5 ppm) and methyl triflate, it is believed to have similar toxic effects based on the evidence available.Methyl trifluoromethanesulfonate is a strong methylating reagent, commonly used for the pre-methylation of polysaccharides under mild basic conditions.Methyl trifluoromethanesulfonate can be used as a methylation reagent:

In the identification of zerovalent sulfur, polysulfides in water wells containing sulfide and polysulfide species within the electrolyte of lithium-sulfur batteries by chromatography-based methods.
In a reaction that involves potassium enolates.
for the conversion of triflates of amines to methyl.