tert-Butyldimethylsilyl trifluoromethanesulfonate ( Tbdms ) Triflate

Tert-Butyldimethylsilyl Trifluoromethanesulfonate ( Tbdms ) Triflate

tert-Butyldimethylsilyl trifluoromethanesulfonate is involved in the introduction of a bulky tert-butyl dimethylsilyl group onto a cis-bis(alkenyl)oxirane used in Cope rearrangement. It is associated with a thiolane and promotes the chalcogenide-Morita-Baylis-Hillman reaction.

Additionally, it serves as an extremely reactive silylating agent. Additionally it is also used to create enol-sillyl the ethers through reaction with lactones and ketones.

This reagent was used to introduce a bulky tert-butyl dimethylsilyl group onto a cis-bis(alkenyl)oxirane facilitating a room temperature Cope rearrangement to a 2-CF3-4,5-dihydrooxepin.

Together with a thiolane promotes a rapid and efficient chalcogenide-Morita-Baylis-Hillman reaction.