C7H15F3O3SSi264.33 g/mol
tert-Butyldimethylsilyl trifluoromethanesulfonate
TBDMS triflate
tert-Butyldimethylsilyl trifluoromethanesulfonate, also known as TBDMSOTf, is a widely used reagent in organic synthesis, mainly for protecting groups.
- CAS No.
- 69739-34-0
- Molecular formula
- C7H15F3O3SSi
- Molecular weight
- 264.33 g/mol
- Purity
- On request
AppearanceColourless Liquid
Price, specification and samples on request · reply within one working day
Made in our own plantsPanoli GIDC, Ankleshwar
Tested in our QC labHPLC · GC · KF and more
COA & SDSShared with every quotation
Grams to multi-tonnesSamples to commercial supply
Overview
It is prepared from triflic acid and tert-butyldimethylsilyl chloride, and is composed of carbon, hydrogen, fluorine, oxygen, sulfur and silicon.
Applications
- Protection of hydroxyl groups in alcohols, carbohydrates and other organic molecules
- Protection of amino groups in amines and amino acids, including peptide synthesis
- Control of stereochemistry by blocking certain reactive sites to favour specific stereoisomers
Technical specifications
| Boiling point | 65-67ºC (12 mmHg) |
|---|---|
| Flash Point | 36ºC |
| Density | 1.15 |
| Water Solubility | Decomposes |
Packaging & storage
Storage
2-8ºC
Safety information
- H226: Flammable liquid and vapour.
- H314: Causes severe skin burns and eye damage.
- H335: May cause respiratory irritation.
Full details are in the Safety Data Sheet, sent with every quotation.
Also known as
TBDMS triflateTBDMSOTftert-Butyldimethylsilyl trifluoromethanesulfonateTrifluoromethanesulfonic acid tert-butyldimethylsilyl ester