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Catalyst

Lifechem Products

4-tertbutyl Benzene Sulfonamide

BUTTPARK 44\03-78 | 4-TERT-BUTYLBENZENESULFONAMIDE | 4-TERT-BUTYLBENZENESULPHONAMIDE | 4-(TERT-BUTYL)BENZENE-1-SULFONAMIDE | P-TERT-BUTYL-BENZENESULFONAMIDE | TertiaryButylBenzeneSulphonamide | 4-(1,1-DIMETHYLETHYL)BENZENESULFONAMIDE

4-Tertbutyl Benzene Sulfonamide

4-tert-Butylbenzenesulfonamide (Bosentan USP Related Compound E) is an intermediate as well as a degradation impurity of the endothelin receptor antagonist Bosentan (B675900).

4-(1,1-Dimethylethyl)benzenesulfonamide; p-tert-butyl-Benzenesulfonamide; NSC 9911; p-(tert-Butyl)phenylsulfonamide; p-tert-Butylbenzenesulfonamide; Bosentan USP Related Compound E

30 ml of ethanolic solution of (E)-3-(4-florophenyl)-1-(4-hydroxyphenyl) prop-2-en-1-one (1.00 mmol) and 4-hydrazinobenzenesulfonamide hydrochloride (1.10 mmol) in presence of a catalytic amount of glacial acetic acide were refluxed for 11 h. The contents of the reaction were monitored by TLC. It was then stirred at the temperature of a room for 12 hours. This solvent then was then removed using a vacuum pump. The solid formed was formed from methanol-ether.

CAS No :

6292-59-7

Formula :

C10H15NO2S

Category:

Product Specification

  • Appearance & Physical State – white solid
  • Molecular weight – 213.29700
  • Boiling point – 337.2ºCat 760 mmHg
  • Flash Point – 157.7ºC

Safety Information As Per GHS

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