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3-Phenyl-1H-Pyrazole-4-Carbaldehyde

3-Phenyl-1H-Pyrazole-4-Carbaldehyde | Lazertinib | 26033-20-5

3-Phenyl-1H-Pyrazole-4-Carbaldehyde is a high-value heterocyclic aldehyde intermediate that plays a critical role in pharmaceutical synthesis, particularly as a key building block in the manufacture of Lazertinib (YH25448). LifeChem Pharma is a trusted bulk manufacturer and supplier of 3-Phenyl-1H-Pyrazole-4-Carbaldehyde, offering pharmaceutical-grade material with consistently high purity of ≥98%.

CAS NO :

26033-20-5

Formula :

C10H8N2O

Weight :

172.18

USE API :

Lazertinib

Category:

Product Specification

  • Appearance & Physical State – White to pale yellow crystalline solid
  • Assay (HPLC) – ≥ 98%
  • Impurity Profile – Controlled as per pharmaceutical standards
  • Moisture Content – ≤ 0.5%
  • Solubility – Soluble in DMSO, ethanol, and common organic solvents
  • Storage Condition – Store in cool, dry, well-ventilated area
  • Packaging – 1 kg / 5 kg / 25 kg HDPE or fiber drum

Safety Information As Per GHS

  • May cause skin and eye irritation upon contact
  • Avoid inhalation of dust or vapors
  • Use appropriate personal protective equipment (gloves, goggles)
  • Keep container tightly sealed
  • Refer to SDS for detailed hazard classification and handling instructions
3-Phenyl-1H-Pyrazole-4-Carbaldehyde is a key heterocyclic aldehyde intermediate widely used in the synthesis of complex pharmaceutical molecules. It features a pyrazole ring bearing a phenyl group at the 3-position and a reactive aldehyde at the 4-position, making it highly suitable for condensation, Knoevenagel, and multi-step pharmaceutical synthesis reactions. This compound serves as a critical building block in the synthesis of Lazertinib (YH25448), a third-generation EGFR tyrosine kinase inhibitor approved for the treatment of EGFR-mutated non-small cell lung cancer (NSCLC). LifeChem Pharma manufactures and supplies this intermediate at pharmaceutical grade with high purity, available in bulk quantities for research and commercial production.

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