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Catalyst

Lifechem Products

trimethylsilyl trifluoromethanesulfonate

trimethylsilyl trifluoromethanesulfonate | Trimethylsilyl Triflate | Tmsotf | Trimethylsilyl Trifluoromethylsulphonate | Trimethylsilyl Trifluoromethylsulfonate | Tms Triflate | Silane Tms-triflate | Trifluoromethanesulphonic Acid Trimethylsilyl Ester | Trimethylsilyl Trifluoromethane-sulphonate | [(Trifluoromethane-sulfonyl)oxy]trimethylsilane | Trifluoromethanesulfonic Acid Trimethylsilyl Ester | Trimethylsilyl Trifluoromethanesulfonate [trimethylsilylating Agent] | Trifluoromethanesulfonic Acid Trimethylsilylester

trimethylsilyl trifluoro methanesulfonate manufacturers in indiaTrimethylsilyl trifluoromethanesulfonate can be used to make powerful Lewis acid, difluoroborontriflate etherate, in an acetonitrile-based solvent. It can also be used in a Dieckmann-life cycle of ester-amides or diesters. It is also used to convert carbonyl compounds into their enol ethers. It can also be used in chemical glycosylation reactions. It is also used in organic synthesis because of its similar reactivity to trimethylsilyl chloride.

Application

For the copper-catalyzed, asymmetrically allylic alkylation of allyl bromides and chlorides (AAA), trimethylsilyl trifluoromethanesulfonate was used in combination with boron trifluoride etherate.

It can be used as follows:

Used as a silylating agent in the synthesis trimethylsilyl-enol (ethers of a-diazoacetic acid)
To activate benzyl ethers and alkyl ethers for the alkylation sulfides.
To facilitate conversion of Diels Alder adducts from Danishefsky’s diene into cyclohexenones, without the formation methoxy ketone byproduct.
A powerful Lewis acid, especially in acetonitrile solvent, is required to prepare difluoroboron Triflate Estate.
Used as a reagent in a Dieckmann-like cycle of ester-amides or esters.

It can also be used as a catalyst:

Acylation of alcohols using acid anhydrides.
Reductive coupling carbonyl compounds and trialkyl silanes in order to create symmetrical ethers
Glycosidation 4-demethoxy daunomycin ones using 1- -acyl–L-daunosamine derivatives.

[Trimethylsilyl trifluoromethanesulfonate]

CAS No :

27607-77-8

EC Number :

248-565-4

Formula :

C4H9F3O3SSi

Product Specification

  • Appearance & Physical State – Clear slightly yellow liquid.
  • Molecular weight – 222.25800
  • Boiling point – 140ºC
  • Flash Point – 25ºC
  • Density – 1.225
  • Vapor Pressure – 2.22E-09mmHg at 25°C
  • Storage Condition – 2-8ºC
  • Water Solubility- Reacts
  • Stability – Stable at room temperature in closed containers under normal storage and handling conditions.

Safety Information As Per GHS

Hazard Class - 3 corrosive

Hazard Statement(s) as per GHS

  • H226: Flammable liquid and vapour.
  • H314: Causes severe skin burns and eye damage.
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