3-(ethyliminomethylideneamino)-N | EDC HCL Manufacturer | Supplier | Exporter | India
EDC HCL Manufacturer | Supplier | Exporter | India | 3-(ethyliminomethylideneamino)-N,N-dimethylp | 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide Hydrochloride [Coupling Agent | wsc hcl | edac hcl | EDC hydrochloride | EDC.HCl | N1-((Ethylimino)methylene)-N3,N3-dimethylpropane-1,3-diamine hydrochloride | 1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide Hydrochloride | 3-(3-Dimethylaminopropyl)-1-Ethylcarbodiimide Hydrochloride | 1-Ethyl-3-(3-dimethyllaminopropyl)carbodiimide hydrochloride | EDAP | 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride | EDCI | EDAC,Hydrochloride
Therefore EDC HCL a water soluble carbodiimide especially designed for coupling reaction in aqueous solution.
Edhcl is a versatile and highly efficient reagent for crosslinking biomolecules such as peptides and proteins. It is a carboxyl activating agent for coupling primary amines to form amide bonds.
It also reacts with phosphate groups to form highly reactive phosphomono-esters and phosphodiesters.
Over the last few years lifechem pharma has been doing extensive research in the Pharma industry prior to further scale up and Synthesis of compound for multiple therapeutic applications.
The findings of lifechem pharma during the research and development was EDHCL further application in anti-osteoporosis compounds.
Compounds for the treatment of neurological diseases.
Still extensive experiment on the edhcl application in other compounds like thromboembolic disease and anti- infective compounds.
In the pre pandemic period application in compounds related to anti-viral and anti- malarial.
From compounds in anti- inflammatory and analgesic compounds to compounds for treatment of cancer.
Again studies and research by the lifechem pharma team found the application of Edhcl in compounds for treatment of multiple therapeutic application and neurological diseases.
Thus the range and scope of its application in compounds for anti- diabetic to anti- malarial resulted in a three to four fold demand world over in the last six to seven years.
The total annual varying demand based on the campaign of various APIs that use EDHCL could be estimated to over 230 mts per annum from 140 mts.
Lifechem pharma has now planned to raise its production capacity step by step within the next six months to increase the productivity by three fold.
This has been further encouraged by the growing list of patrons over the last few years.
N-(3-Dimethylaminopropyl)-N′-Ethylcarbodiimide Hydrochloride ( EDC HCL )
N-(3-Dimethylaminopropyl)-N’-Ethylcarbodiimide Hydrochloride ( EDC HCL ) is being used for the synthesis of amides. EDC.HCl is also used as a coupling agent in the preparation of esters from carboxylic acids using Dimethylaminopropyl as the catalyst. It is a water-soluble carbodiimide extensively used in the coupling of peptides.
It is a simple to handle solid with high solubility liquids (>200gl) as well as organic solvents like dimethylformamide, dichloromethane, and tetrahydrofuran.
EDC*HCl replaced N, N-Dimethylaminopropyl (DCC) in solution-phase peptide synthesis because its urea is highly soluble in aqueous solutions, and so is easily removed by an aqueous workup.
As well as being used for the synthesis of amides, EDC*HCl is also used as a coupling agent in the preparation of esters from carboxylic acids using Dimethylaminopropyl as the catalyst.
Combinations of EDC*HCl with potassium salts from oximes make novel and distinct coupling cocktails that can be used to create hindered peptides, such as Aib-enkephaline pentapeptide.
EDC HCL Manufacturer | Supplier | Exporter | Importer
EDC-HCl ; CAS Number: 25952-53-8 ; Molecular Weight: 191.70 ; Beilstein: 5764110 ; MDL number: MFCD00012503.
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- Appearance & Physical State – white to off-white powder
- Molecular weight – 191.70200
- Boiling point – 269.1ºC at 760 mmHg
- Flash Point – 107.9ºC
- Density – 0.877 g/mL at 20ºC(lit.)
- Vapor Pressure – 0.171mmHg at 25°C
- Storage Condition – -20ºC
- Water Solubility- Soluble
Safety Information As Per GHS
Hazard Statement(s) as per GHS | EDC HCL
- H315: Causes skin irritation.
- H318: Causes serious eye damage.
- H335: May cause respiratory irritation