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Cyclopropylmethyl Bromide

Cyclopropylmethyl bromide, also known as bromocyclopropane or bromomethylcyclopropane, is a chemical compound with the molecular formula C4H7Br. It belongs to the class of organic compounds known as organobromides, which are compounds containing a carbon-bromine bond.

Introduction of Cyclopropylmethyl Bromide

In the realm of organic chemistry, certain compounds captivate the imagination of both researchers and enthusiasts alike. Among these is cyclopropylmethy-bromide, a small yet intriguing molecule with a distinct structure and a myriad of applications. In this blog post, we delve into the world of cyclopropylmethylbromide, exploring its chemistry, properties, and diverse uses in the field of organic synthesis.

Cyclopropylmethyl Bromide Understanding the Structure:

At first glance, cyclopropylmethylbromide may seem unassuming, but its structure holds the key to its reactivity and utility. Comprising a cyclopropyl ring attached to a methyl group and a bromine atom, this compound embodies the fusion of simplicity and complexity. The strained three-membered cyclopropyl ring imparts unique properties to the molecule, making it a valuable building block in organic synthesis.

Applications in Organic Synthesis: Cyclopropylmethyl Bromide

The versatility of cyclopropylmethylbromide makes it indispensable in modern organic synthesis. It serves as a key intermediate in the production of pharmaceuticals, agrochemicals, and fine chemicals. Chemists utilize it to introduce cyclopropyl motifs, a structural motif found in many biologically active compounds, into target molecules. Furthermore, its ability to undergo stereo controlled reactions enables the synthesis of chiral compounds, crucial in drug discovery and development.


Product Specification

Property Description
Chemical Formula C4H7Br
Molecular Weight Approximately 137.00 g/mol
Physical State Colorless to pale yellow liquid
Cas no  7051-34-5
Melting Point -93°C (-135°F)
Boiling Point 106°C (223°F)
Solubility Soluble in organic solvents, insoluble in water
Hazard Class Highly flammable, toxic
Handling Precautions Handle with care, use in well-ventilated area, wear appropriate PPE
Storage Store in tightly sealed container away from heat and ignition sources

Safety Information As Per GHS

Safety Parameter Recommendations
Personal Protective Equipment (PPE) Wear safety goggles, gloves, lab coat, and closed-toe shoes when handling cyclopropylmethyl bromide.
Ventilation Work in a well-ventilated area, such as a fume hood, to minimize inhalation exposure to vapors. Ensure proper ventilation.
Handling Precautions Handle with care to avoid skin contact and inhalation of vapors. Use syringes or pipettes for accurate transfer.
Storage Store in a tightly sealed container away from heat, ignition sources, and incompatible materials. Follow manufacturer guidelines.
Emergency Procedures Familiarize with emergency procedures for exposure or spills. Have spill control materials readily available.
First Aid In case of skin contact, wash affected area with water. Seek medical attention for inhalation or ingestion.
Chemical Compatibility Be aware of compatibility with other substances to prevent reactions. Consult safety data sheets (SDS) for guidance.
Training Ensure personnel are trained in safe handling and emergency response protocols. Provide regular safety updates and training.
Waste Disposal Dispose of according to local regulations for hazardous waste. Do not pour down the drain.
Risk Assessment Conduct a thorough risk assessment considering toxicity, flammability, and reactivity. Implement appropriate control measures.