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Propanephosphonic acid anhydride [50 solution in DMF]

Propanephosphonic acid anhydride (50% solution in DMF)

50 solution in DMF – Propylphosphonic anhydride is a highly reactive cyclic anhydride commonly used as a coupling agent and water scavenger.

Application

Coupling reagent for peptide synthesis; Preparation of other amides; Synthesis of esters (depsipeptides)

Features and Benefits

  • Some of its unique features include:
  • Broad functional group tolerance
  • Low epimerization tendency
  • By-products are water-soluble
  • High yield and purity

CAS No :

68957-94-8
EC Number :

422-210-5

Category:

Product Specification

  • Grade  technical
  • Quality Level  100
  • Form  solution
  • Concentration  ~50% in DMF
  • SMILES string  CCCP1(=O)OP(=O)(CCC)OP(=O)(CCC)O1
  • InChI  1S/C9H21O6P3/c1-4-7-16(10)13-17(11,8-5-2)15-18(12,14-16)9-6-3/h4-9H2,1-3H3
  • InChI key  PAQZWJGSJMLPMG-UHFFFAOYSA-N

Safety Information As Per GHS

  • Hazard Classifications  Eye Dam. 1 - Met. Corr. 1 - Repr. 1B - Skin Corr. 1B - Skin Sens. 1
  • Signal Word  Danger
  • Storage Class Code  6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
  • Personal Protective Equipment  dust mask type N95 (US), Eyeshields, Gloves
  • Flash Point(C)  62 °C
  • Flash Point(F)  143.6 °F

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